Research Project:
Yr. 2 IHSFC Voucher - Development of pancreatic cell specific lncRNA MALA Tl null mouse model for analysis diabetogenic environmental chemicals.

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dc.contributor.departmentVeterinary - Physiology & Pharmacology
dc.contributor.memberTAMU
dc.contributor.pdachttps://hdl.handle.net/20.500.14641/614
dc.contributor.sponsorDHHS-NIH-National Institute of Environmental Health Sciences
dc.creator.copiThreadgill, David
dc.creator.copiHillhouse, Andrew
dc.creator.copiCai, James
dc.creator.piTian, Yanan
dc.date2021-09-30
dc.date.accessioned2025-03-20T17:45:42Z
dc.date.available2025-03-20T17:45:42Z
dc.descriptionIntrasystem Agreement
dc.description.abstractProject description: To investigate the function of the MALAT1 in cells and to study the effects of PCB126 and other “dioxin like” xenobiotics on the cell population in the absence of MALAT1 in vivo, we planned to develop the tissue/organ specific targeting at pancreatic cells as well as other organs. MALAT1 knockout mouse model by CRISPR/Cas9 technology with insertion of loxP franking the Malat1-201 which is the longest the transcripts of 4 known transcripts of the Malat1 mouse gene.
dc.description.chainOfCustody2025-03-20T17:46:14.272583443 Mary Nelson (acea4c6e-ad9f-4f41-927d-a3256f722f9c) added Tian, Yanan (2518931c-a297-4b47-9233-05c91313c1f7) to null (38cceeea-e217-47cf-8144-4eeffdf185d2)en
dc.identifier.otherM2101908
dc.identifier.urihttps://hdl.handle.net/20.500.14641/1021
dc.relation.profileurlhttps://scholars.library.tamu.edu/vivo/display/n7f54d80b
dc.titleYr. 2 IHSFC Voucher - Development of pancreatic cell specific lncRNA MALA Tl null mouse model for analysis diabetogenic environmental chemicals.
dc.title.projectYr. 2 IHSFC Voucher - Development of pancreatic cell specific lncRNA MALA Tl null mouse model for analysis diabetogenic environmental chemicals.
dspace.entity.typeResearchProject
local.awardNumberP30ES029067
local.pdac.nameTian, Yanan
local.projectStatusTerminated

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